  {"id":75244,"date":"2020-01-06T00:00:00","date_gmt":"2020-01-06T00:00:00","guid":{"rendered":"https:\/\/www.uri.edu\/news-draft\/uncategorized\/uri-baycare-in-florida-and-butler-hospital-team-up-to-test-retinal-scanning-for-early-detection-of-alzheimers-disease\/"},"modified":"2022-07-05T20:05:16","modified_gmt":"2022-07-05T20:05:16","slug":"uri-baycare-in-florida-and-butler-hospital-team-up-to-test-retinal-scanning-for-early-detection-of-alzheimers-disease","status":"publish","type":"post","link":"https:\/\/www.uri.edu\/news\/2020\/01\/uri-baycare-in-florida-and-butler-hospital-team-up-to-test-retinal-scanning-for-early-detection-of-alzheimers-disease\/","title":{"rendered":"溏心vlog免费B站, BayCare in Florida and Butler Hospital team up to test retinal scanning for early detection of Alzheimer\u2019s disease"},"content":{"rendered":"\n<p>KINGSTON, R.I. &#8212; Jan. 6, 2020 &#8212; The <a href=\"https:\/\/www.uri.edu\/\">溏心vlog免费B站,<\/a> in collaboration with <a href=\"https:\/\/baycare.org\/\">BayCare Health System<\/a> in Florida and <a href=\"http:\/\/www.butler.org\/memory\/\">The Memory and Aging Program at Butler Hospital<\/a>, an affiliate of The Warren Alpert Medical School of Brown University, is launching a clinical trial of retinal screening processes that could help clinicians detect Alzheimer\u2019s disease possibly two or more decades before patients develop life-altering clinical symptoms.<\/p>\n\n\n\n<p>The five-year, $5 million Atlas of Retinal Imaging in Alzheimer\u2019s Study (ARIAS) is sponsored by BayCare Health System\u2019s Morton Plant Hospital and St. Anthony\u2019s Hospital and funded largely by Morton Plant Mease Health Care Foundation and St. Anthony\u2019s Hospital Foundation in Pinellas County, Florida.<\/p>\n\n\n\n<p>Principal investigators for the study are Peter Snyder, Ph.D., 溏心vlog免费B站 vice president for research and economic development and professor of biomedical and pharmaceutical sciences, and Stuart Sinoff, M.D., who specializes in neuro-ophthalmology and is a medical director of Neurosciences for BayCare Health System\u2019s West Region in Pinellas County. According to the two researchers, the objective is to create a gold standard reference database of structural, anatomic and functional imaging of the retina to enable the identification and development of sensitive and reliable markers of early Alzheimer\u2019s disease and\/or risk progression.<\/p>\n\n\n\n<figure class=\"wp-block-gallery columns-4 wp-block-gallery-1 is-layout-flex wp-block-gallery-is-layout-flex\"><ul class=\"blocks-gallery-grid\"><li class=\"blocks-gallery-item\"><figure><img loading=\"lazy\" decoding=\"async\" width=\"610\" height=\"171\" src=\"https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/ARIAS-logo-new-idea.jpg\" alt=\"\" data-id=\"75245\" data-full-url=\"https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/ARIAS-logo-new-idea.jpg\" data-link=\"https:\/\/www.uri.edu\/news\/2020\/01\/uri-baycare-in-florida-and-butler-hospital-team-up-to-test-retinal-scanning-for-early-detection-of-alzheimers-disease\/arias-logo-new-idea\/\" class=\"wp-image-75245\" srcset=\"https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/ARIAS-logo-new-idea.jpg 610w, https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/ARIAS-logo-new-idea-300x84.jpg 300w, https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/ARIAS-logo-new-idea-364x102.jpg 364w, https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/ARIAS-logo-new-idea-500x140.jpg 500w\" sizes=\"auto, (max-width: 610px) 100vw, 610px\" \/><\/figure><\/li><li class=\"blocks-gallery-item\"><figure><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"400\" src=\"https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/溏心vlog免费B站-Logo-1024x400.jpg\" alt=\"\" data-id=\"75246\" data-full-url=\"https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/溏心vlog免费B站-Logo-scaled.jpg\" data-link=\"https:\/\/www.uri.edu\/news\/2020\/01\/uri-baycare-in-florida-and-butler-hospital-team-up-to-test-retinal-scanning-for-early-detection-of-alzheimers-disease\/logo-282\/\" class=\"wp-image-75246\" srcset=\"https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/溏心vlog免费B站-Logo-1024x400.jpg 1024w, https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/溏心vlog免费B站-Logo-300x117.jpg 300w, https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/溏心vlog免费B站-Logo-768x300.jpg 768w, https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/溏心vlog免费B站-Logo-1536x600.jpg 1536w, https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/溏心vlog免费B站-Logo-2048x800.jpg 2048w, https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/溏心vlog免费B站-Logo-364x142.jpg 364w, https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/溏心vlog免费B站-Logo-500x195.jpg 500w, https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/溏心vlog免费B站-Logo-1000x391.jpg 1000w, https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/溏心vlog免费B站-Logo-1280x500.jpg 1280w, https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/溏心vlog免费B站-Logo-2000x781.jpg 2000w, https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/溏心vlog免费B站-Logo-scaled.jpg 2560w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure><\/li><li class=\"blocks-gallery-item\"><figure><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"334\" src=\"https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/BayCare-1024x334.jpg\" alt=\"\" data-id=\"75247\" data-full-url=\"https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/BayCare.jpg\" data-link=\"https:\/\/www.uri.edu\/news\/2020\/01\/uri-baycare-in-florida-and-butler-hospital-team-up-to-test-retinal-scanning-for-early-detection-of-alzheimers-disease\/print\/\" class=\"wp-image-75247\" srcset=\"https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/BayCare-1024x334.jpg 1024w, https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/BayCare-300x98.jpg 300w, https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/BayCare-768x250.jpg 768w, https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/BayCare-364x119.jpg 364w, https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/BayCare-500x163.jpg 500w, https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/BayCare-1000x326.jpg 1000w, https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/BayCare.jpg 1200w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure><\/li><li class=\"blocks-gallery-item\"><figure><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"205\" src=\"https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/Butler-175-color.jpg\" alt=\"\" data-id=\"75253\" data-full-url=\"https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/Butler-175-color.jpg\" data-link=\"https:\/\/www.uri.edu\/news\/2020\/01\/uri-baycare-in-florida-and-butler-hospital-team-up-to-test-retinal-scanning-for-early-detection-of-alzheimers-disease\/butler-175-color\/\" class=\"wp-image-75253\" srcset=\"https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/Butler-175-color.jpg 600w, https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/Butler-175-color-300x103.jpg 300w, https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/Butler-175-color-364x124.jpg 364w, https:\/\/www.uri.edu\/news\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/Butler-175-color-500x171.jpg 500w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/figure><\/li><\/ul><\/figure>\n\n\n\n<figure class=\"wp-block-embed aligncenter is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<div class=\"oembed oembed-youtube-com\" style=\"\" data-url=\"https:\/\/www.youtube.com\/watch?v=wWTeFsjkyfU&#038;feature=youtu.be\"><iframe loading=\"lazy\" title=\"Retinal Scanning | Early Detection of Alzheimer&#039;s Disease\" width=\"1000\" height=\"563\" src=\"https:\/\/www.youtube.com\/embed\/wWTeFsjkyfU?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen><\/iframe><\/div>\n<\/div><\/figure>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"alignright is-resized\"><a href=\"https:\/\/www.uri.edu\/news-draft\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/ArthurSnyderAlber-0020.jpg\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.uri.edu\/news-draft\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/ArthurSnyderAlber-0020.jpg\" alt=\"溏心vlog免费B站 TEAM FOR ARIAS CLINICAL TRIAL\" class=\"wp-image-55781\" width=\"600\" height=\"388\" \/><\/a><figcaption>溏心vlog免费B站 TEAM FOR ARIAS CLINICAL TRIAL: From left are Edmund Arthur, doctor of optometry and Ph.D., co-principal investigator Peter Snyder, Ph.D., 溏心vlog免费B站 vice president for research and economic development and professor of biomedical and pharmaceutical sciences, and Jessica Alber, Ph.D., Ryan research assistant professor of neuroscience at 溏心vlog免费B站. 溏心vlog免费B站 photo by Michael Salerno<\/figcaption><\/figure><\/div>\n\n\n\n<p>The problem now is that one of the central diagnostic tools for Alzheimer\u2019s disease, positron emission tomography (PET) scanning devices, which can detect amyloid protein plaques (a toxic protein that interferes with normal brain function), are expensive. While they can detect brain pathology related to Alzheimer\u2019s disease well before symptoms develop, the costs for such machines run into the millions and one test currently costs as much as $4,500. So, PET scans are often done after patients become symptomatic and when drug therapies may no longer be effective in slowing the disease in its earliest stages. Snyder also notes that a large portion of the world\u2019s population does not have access to PET scans.<\/p>\n\n\n\n<p>\u201cWhen our study is completed, we want to make the technology available so that optometrists and ophthalmologists could screen for the retinal biomarkers we believe are associated with Alzheimer\u2019s disease and watch them over time,\u201d Snyder said. \u201cIf clinicians see changes, they could refer their patients to specialists early on. We believe this could significantly lower the cost of testing. We may then identify more people in the very earliest stage of the disease, and our drug therapies are likely to be more effective at that point and before decades of slow disease progression.\u201d<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"alignright is-resized\"><a href=\"https:\/\/www.uri.edu\/news-draft\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/Sinoff-0238.jpg\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.uri.edu\/news-draft\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/Sinoff-0238.jpg\" alt=\"CO-LEADER OF ARIAS: Stuart Sinoff, M.D\" class=\"wp-image-55788\" width=\"322\" height=\"450\" \/><\/a><figcaption>CO-LEADER OF ARIAS: Stuart Sinoff, M.D., who specializes in neuro-ophthalmology and is a medical director of Neurosciences for BayCare Health System\u2019s West Region in Pinellas County, Florida. Photo courtesy BayCare Health System<\/figcaption><\/figure><\/div>\n\n\n\n<p>Snyder and Sinoff are working with Stephen Salloway, M.D., director of Neurology and the Memory and Aging Program, Butler Hospital and Martin M. Zucker professor of psychiatry and human behavior, professor of neurology, Alpert Medical School of Brown University, who is a world-leading clinical trials expert in Alzheimer\u2019s disease, and Jessica Alber, Ph.D., Ryan assistant professor of research and cognitive neuroscientist at 溏心vlog免费B站, who completed her post-doctoral fellowship in the Department of Psychiatry and Human Behavior at the Alpert Medical School of Brown University with Salloway and Snyder. There are 14 other collaborators, including neuropsychologists, social workers, optometrists, nursing staff and students.<\/p>\n\n\n\n<p>\u201cWe are very grateful to be working with some of the leading researchers in the field from BayCare, Butler Hospital and Brown University on this important study,\u201d Snyder said. \u201cDrs. Sinoff, Salloway, Alber and I have already been publishing together in this area.&nbsp; I am honored that Dr. Salloway is leading our clinical site at Butler Hospital, and our work there will be tightly coordinated with the efforts on this study at BayCare\u2019s two flagship hospitals in Florida.\u201d<\/p>\n\n\n\n<p>\u201cModern health care is perhaps a victim of its own success,\u201d Sinoff said. \u201cWith an ever increasing human lifespan, we find ourselves faced with a rapidly expanding group of people in cognitive decline.&nbsp; And there\u2019s also the unanticipated ballooning of the price tag for dementia care. ARIAS is structured to address both.<\/p>\n\n\n\n<p>\u201cSpeaking for the Florida sites, Morton Plant Hospital and St. Anthony\u2019s Hospital, and with special homage to the generous support from the Morton Plant Mease Health Care Foundation who have made ARIAS possible, I am truly honored to work with Drs. Snyder, Alber and Salloway, partnering to establish a cost-effective biomarker panel that will identify people in the earliest stages of Alzheimer\u2019s disease possible.\u201d<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"alignright is-resized\"><a href=\"https:\/\/www.uri.edu\/news-draft\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/SALLOWAY-15.jpg\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.uri.edu\/news-draft\/wp-content\/uploads\/news\/sites\/16\/2021\/05\/SALLOWAY-15.jpg\" alt=\"STEPHEN SALLOWAY, M.D.,\" class=\"wp-image-55793\" width=\"342\" height=\"450\" \/><\/a><figcaption>STEPHEN SALLOWAY, M.D., director of Neurology and the Memory and Aging Program, Butler Hospital, member of the ARIAS team. 溏心vlog免费B站 photo by Michael Salerno<\/figcaption><\/figure><\/div>\n\n\n\n<p>\u201cWe are excited to be participating with the ARIAS team from 溏心vlog免费B站 and BayCare on this landmark study,\u201d Salloway said.&nbsp; \u201cThe ARIAS study closely aligns with the mission of Butler Hospital and Brown University to develop new approaches to detect Alzheimer\u2019s risk early and keep the brain healthy so memory loss never occurs.\u201d<\/p>\n\n\n\n<p>The ARIAS study is unique in its focus on preclinical stage disease, and its emphasis on viewing the retina as a complex biological system, requiring that researchers view the retina in many different ways at the same time.&nbsp; For example, pictures of the retinas of participants will be taken with very special blue, green and infrared lasers that are completely safe, but will allow for a microscopic look at its anatomy, changes in pigment chemicals as well as the movement of red blood cells in the retina.<\/p>\n\n\n\n<p>\u201cThe cells in the neuronal layers of the retina are the same types as cells in the brain that are attacked by the disease, so cell changes in the retina might reflect the same changes that are happening in the brain,\u201d Snyder said. \u201cWe can look more easily in the retina to see the effects of disease on the way blood is carried to brain and retinal cells.&nbsp; We are also using a very new laser imaging technique that makes the chemical pigments in the retina fluoresce, and we think atypical changes in the amount of these chemicals might signal high risk for Alzheimer\u2019s disease.\u201d<\/p>\n\n\n\n<p>The ARIAS study will enroll 330 individuals between the ages of 55 and 80 years old, ranging from very healthy and low-risk adults, to persons with concerns about their memory, as well as patients with mild Alzheimer\u2019s disease.&nbsp; Each participant will be examined at four different points over a three-year period, and each study visit includes an eye exam, a medical history discussion, some tests of how people think and how well they remember new information, the retinal imaging that is very much like the kind done at the eye doctor\u2019s office, and measures of mood, walking and balancing, sleep habits and other types of medical information.<\/p>\n\n\n\n<p>If you are interested in donating your time to participate in this important study, and if you live near Providence, Rhode Island, please contact the Butler Alzheimer\u2019s Prevention Registry<a href=\"http:\/\/butler.org\/alzregistry\"> butler.org\/alzregistry<\/a> or call 401-455-6402.<\/p>\n\n\n\n<p>If you live near Tampa, Clearwater or St. Petersburg in Florida, and you are interested in finding out more about the study, please call Catrina Montgomery at 727-298-6077.<\/p>\n\n\n\n<p><strong>溏心vlog免费B站 the 溏心vlog免费B站<\/strong><\/p>\n\n\n\n<p>The <a href=\"https:\/\/www.uri.edu\/\">溏心vlog免费B站<\/a> is a competitive and highly regarded public institution in New England and beyond. Founded in 1892, the University is the principal public flagship research and graduate institution in Rhode Island, enrolling about 14,650 undergraduate students and more than 2,240 graduate students. The University is known regionally and worldwide for its big ideas and pioneering research in air, water, and ground pollution; biotechnology and life sciences; engineering, marine sciences, forensic sciences, neuroscience, pharmaceuticals, the behavioral sciences and public health promotion.&nbsp;溏心vlog免费B站 is home to&nbsp;The George &amp; Anne Ryan Institute for Neuroscience, which brings together a pioneering team of scientists noted for their contributions to under-explored factors in brain health\u2014including the roles of inflammation, the immune system, and blood vessels in the development of neurodegenerative diseases like Alzheimer\u2019s.<\/p>\n\n\n\n<p><strong>溏心vlog免费B站 BayCare Health System<\/strong><\/p>\n\n\n\n<p>BayCare is a leading not-for-profit health care system that connects individuals and families to a wide range of services at 15 hospitals and hundreds of other convenient locations throughout the Tampa Bay and central Florida regions. Inpatient and outpatient services include acute care, primary care, imaging, laboratory, behavioral health, home care, and wellness. Our mission is to improve the health of all we serve through community-owned, health care services that set the standard for high-quality, compassionate care. For more information, visit<a href=\"http:\/\/www.baycare.org\"> www.BayCare.org<\/a>.<\/p>\n\n\n\n<p><strong>溏心vlog免费B站 Butler Hospital<\/strong><\/p>\n\n\n\n<p>Butler Hospital, a member of Care New England, is the only private, nonprofit psychiatric and substance abuse hospital serving adults, seniors and adolescents in Rhode Island and southeastern New England. Founded in 1844, it was the first hospital in Rhode Island and has earned a reputation as the leading provider of innovative psychiatric treatments in the region. The Major Affiliated Teaching Hospital for Psychiatry and Behavioral Health at The Warren Alpert Medical School of Brown University, Butler is recognized worldwide as a pioneer in conducting cutting-edge research. For more information, visit<a href=\"http:\/\/www.butler.org\/\"> butler.org<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>KINGSTON, R.I. &#8212; Jan. 6, 2020 &#8212; The 溏心vlog免费B站, in collaboration with BayCare Health System in Florida and The Memory and Aging Program at Butler Hospital, an affiliate of The Warren Alpert Medical School of Brown University, is launching a clinical trial of retinal screening processes that could help clinicians detect Alzheimer\u2019s [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":75252,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[],"class_list":["post-75244","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-archives"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/posts\/75244","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/comments?post=75244"}],"version-history":[{"count":2,"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/posts\/75244\/revisions"}],"predecessor-version":[{"id":80067,"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/posts\/75244\/revisions\/80067"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/media\/75252"}],"wp:attachment":[{"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/media?parent=75244"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/categories?post=75244"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/tags?post=75244"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}