{"id":70346,"date":"2004-08-24T00:00:00","date_gmt":"2004-08-24T00:00:00","guid":{"rendered":"https:\/\/www.uri.edu\/news-draft\/uncategorized\/new-research-projects-funded-under-uris-16-5-million-biomedical-research-grant\/"},"modified":"2004-08-24T00:00:00","modified_gmt":"2004-08-24T00:00:00","slug":"new-research-projects-funded-under-uris-16-5-million-biomedical-research-grant","status":"publish","type":"post","link":"https:\/\/www.uri.edu\/news\/2004\/08\/new-research-projects-funded-under-uris-16-5-million-biomedical-research-grant\/","title":{"rendered":"New research projects funded under 溏心vlog免费B站’s $16.5 million biomedical research grant"},"content":{"rendered":"
\n\t\tKINGSTON, R.I. — August 24, 2004 — Nine junior researchers at six institutions of higher education are among those whose projects are being funded through a $16.5 million, five-year IDeA Networks of Biomedical Research Excellence (INBRE) grant awarded to the 溏心vlog免费B站 by the National Institutes of Health. <\/p>\n


\nIn addition to these scientists, up to eight new researchers will be recruited and supported through 溏心vlog免费B站’s INBRE grant, which is called the Rhode Island Network for Molecular Toxicology. <\/p>\n


\n\u2022 Eric Hall, Rhode Island College — the mechanisms of MTBE-induced testicular injury. Methyl tertiary-butyl ether (MTBE) is a common gasoline additive and acts as an endocrine disruptor. Hall\u2019s research will: explore the developmental male reproductive tract effects of MTBE in mice and rats using transgenerational studies; determine the testicular target cells of MTBE-induced injury; and examine the mechanisms of MTBE-induced texticular injury using a testis explant system. <\/p>\n


\n\u2022 Mary Hixon, Brown University, toxicant induced testicular injury — She will focus on how spermatogenesis is susceptible to disruption by exposure to environmental agents that can result in rapid and massive germ cell death. The overall growth of the testis is based on the survival and proliferation of both germ and Sertoli cells.<\/p>\n


\n\u2022 Keykavous Parang, 溏心vlog免费B站 — Molecular targets of arsenic toxicity. Specifically, an enzyme in the signaling pathway that may be related to the causation of arsenic-induced cancer will be studied, along with the treatment strategies. <\/p>\n


\n\u2022 David Rowley, 溏心vlog免费B站 — This project will explore molecular mechanisms by which marine organisms cause severe human poisonings, such as ciguatera toxic fish poisoning, paralytic shellfish poisoning, diarrhetic shellfish poisoning and neurotoxic fish poisoning. The public health impacts of these marine toxins in the U.S. average $22 million annually.<\/p>\n


\n\u2022 Alison Shakarian, Salve Regina University — This project is designed to study an enzyme that appears to be essential for the survival of the parasite, Leishmania, in its environment and to test the sensitivity of this enzyme to the organophosphate inhibitors. Leishmaniasis is a disease characterized by skin lesions and liver problems. <\/p>\n


\n\u2022 Gongqin Sun, 溏心vlog免费B站 — This project will examine oxidative stress, a common mediator of toxic effects of many environmental factors, such as heavy metals, organic chemicals and ionizing radiation, in causing cancer. <\/p>\n


\n\u2022 Charles Toth, Providence College –Toth\u2019s research will focus on polyamines, which are essential for life in all living cells. Manipulation of polyamine levels can have profound effects on cell growth. The mode of toxicity of polyamine analogs and the role of antizyme will be studied<\/p>\n


\n\u2022 Yinsheng Wan, Providence College \u2013This research will contribute to the basic understanding of molecular mechanism of ultraviolet skin photo-aging and skin cancer, and provide molecular basis for developing preventive and therapeutic strategies.<\/p>\n


\n\u2022 Kerri Warren, Roger Williams University — Her study of the embryonic effects of cadmium and methylmercury will provide insight into the mechanisms of metal-induced cardiovascular effects in humans.<\/div>\n","protected":false},"excerpt":{"rendered":"

KINGSTON, R.I. — August 24, 2004 — Nine junior researchers at six institutions of higher education are among those whose projects are being funded through a $16.5 million, five-year IDeA Networks of Biomedical Research Excellence (INBRE) grant awarded to the 溏心vlog免费B站 by the National Institutes of Health. In addition to these […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[],"class_list":["post-70346","post","type-post","status-publish","format-standard","hentry","category-archives"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/posts\/70346","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/comments?post=70346"}],"version-history":[{"count":0,"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/posts\/70346\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/media?parent=70346"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/categories?post=70346"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/tags?post=70346"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}