{"id":60197,"date":"2012-06-21T00:00:00","date_gmt":"2012-06-21T00:00:00","guid":{"rendered":"https:\/\/www.uri.edu\/news-draft\/uncategorized\/uri-researchers-receive-excellence-award-for-patented-method-of-vaccinating-fish\/"},"modified":"2012-06-21T00:00:00","modified_gmt":"2012-06-21T00:00:00","slug":"uri-researchers-receive-excellence-award-for-patented-method-of-vaccinating-fish","status":"publish","type":"post","link":"https:\/\/www.uri.edu\/news\/2012\/06\/uri-researchers-receive-excellence-award-for-patented-method-of-vaccinating-fish\/","title":{"rendered":"溏心vlog免费B站 researchers receive excellence award for patented method of vaccinating fish"},"content":{"rendered":"
\n\t\tKINGSTON, R.I. \u2013 June 21, 2012 \u2013 One of the greatest challenges for the aquaculture industry is health management. A disease outbreak can spread quickly and kill every last fish. And because antibiotic use is restricted at fish farms, one of the best options for maintaining a healthy fish population is the use of vaccines.<\/p>\n


\n\t\u201cDNA vaccines are a novel type of vaccine that have proven to be very effective at preventing disease, but only when delivered by injection into the muscle of the fish or by shooting them with gold particles using a gene gun,\u201d explained Marta Gomez-Chiarri, professor of fisheries at the 溏心vlog免费B站. \u201cBut vaccinating one fish at a time is very expensive.\u201d<\/p>\n


\n\tGomez-Chiarri and fellow 溏心vlog免费B站 Professor David Nelson have developed a simple and inexpensive vaccine delivery system that involves the immersion of the fish in a vaccine bath. The 溏心vlog免费B站 scientists were awarded a patent for their discovery, and at a ceremony last month they received the Intellectual Property Award of Excellence from the 溏心vlog免费B站 Division of Research and Economic Development.<\/p>\n


\n\t\u201cYou can treat a lot of fish very quickly by immersion,\u201d said Gomez-Chiarri, a resident of Jamestown. \u201cInitially, too little of the DNA vaccine was getting into the fish to be effective, perhaps because it was getting degraded in the water or in the gut of the fish. So we found a way of putting the vaccine inside bacteria that are good at getting into the fish and then bathing the fish in the bacterial solution.\u201d<\/p>\n


\n\tThe key was getting the vaccine into the proper tissues so the fish\u2019s immune system recognizes it and produces an appropriate immune response. But that also raised concerns.<\/p>\n


\n\t\u201cFish pathogens are really good at getting into fish, but we have to have a way to attenuate their virulence so they can deliver the vaccine without causing disease,\u201d she said. \u201cThat\u2019s the fine balance.\u201d<\/p>\n


\n\tGomez-Chiarri said there is still a lot of work to do before the method is commercialized. The delivery method was initially tested using a vaccine against a trout virus that is common in aquaculture facilities in the Pacific Northwest, and she hopes to test a refined version of the vaccine there again soon.<\/p>\n


\n\t\u201cYou usually target diseases that have a big economic impact and affect a variety of different species,\u201d said Gomez-Chiarri. \u201cMany vaccine companies, for example, are trying to help the salmon industry in Chile, which is impacted by a flu-like virus that causes infectious salmon anemia.\u201d<\/p>\n


\n\tApplying for a patent can be a long and expensive process. It took almost 10 years for the U.S. Patent Office to award the patent to Gomez-Chiarri and Nelson for their vaccine delivery system.<\/p>\n


\n\t\u201cOur next step is to try using a few more kinds of bacteria to put the vaccine into, and then compare the delivery by injection with delivery by immersion,\u201d she said. \u201cHopefully we\u2019ll find a company that is interested in our work and willing to provide funding for us to continue to make it better.\u201d<\/p>\n


\n溏心vlog免费B站 Department of Communications & Marketing photo by Michael Salerno Photography.<\/div>\n","protected":false},"excerpt":{"rendered":"

KINGSTON, R.I. \u2013 June 21, 2012 \u2013 One of the greatest challenges for the aquaculture industry is health management. A disease outbreak can spread quickly and kill every last fish. And because antibiotic use is restricted at fish farms, one of the best options for maintaining a healthy fish population is the use of vaccines. […]<\/p>\n","protected":false},"author":2,"featured_media":60199,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[],"class_list":["post-60197","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-archives"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/posts\/60197","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/comments?post=60197"}],"version-history":[{"count":0,"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/posts\/60197\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/media\/60199"}],"wp:attachment":[{"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/media?parent=60197"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/categories?post=60197"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/tags?post=60197"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}