{"id":57632,"date":"2015-10-15T00:00:00","date_gmt":"2015-10-15T00:00:00","guid":{"rendered":"https:\/\/www.uri.edu\/news-draft\/uncategorized\/uri-researcher-says-class-of-cranberry-carbohydrates-could-improve-treatment-of-urinary-tract-infections\/"},"modified":"2015-10-15T00:00:00","modified_gmt":"2015-10-15T00:00:00","slug":"uri-researcher-says-class-of-cranberry-carbohydrates-could-improve-treatment-of-urinary-tract-infections","status":"publish","type":"post","link":"https:\/\/www.uri.edu\/news\/2015\/10\/uri-researcher-says-class-of-cranberry-carbohydrates-could-improve-treatment-of-urinary-tract-infections\/","title":{"rendered":"溏心vlog免费B站 researcher says class of cranberry carbohydrates could improve treatment of urinary tract infections"},"content":{"rendered":"
\n\t\tLaboratory tests at College of Pharmacy show antibiotic treatment enhanced<\/b><\/p>\n


\n\tKINGSTON, R.I. \u2013 October 15, 2015 \u2013 A 溏心vlog免费B站 researcher and his team in the College of Pharmacy have found that a class of complex carbohydrates could enhance treatment of urinary tract infections.<\/p>\n


\n\tBiomedical Science Professor David Rowley\u2019s findings appear in a recent issue of the Journal of Functional Foods, which is published by the International Society for Nutraceuticals and Functional Foods. The research is sponsored by Ocean Spray, a cooperative of more than 700 cranberry and grapefruit growers based in Lakeville, Mass.<\/p>\n


\nAmong Rowley\u2019s team are 溏心vlog免费B站 Associate Professor of Biomedical Science Navindra Seeram, who has been cited internationally for his research on blueberries, pomegranate and pure maple syrup and Pharmacy Professor Kerry LaPlante, nationally recognized for her work in the treatment, virulence inhibition, control and prevention of methicillin -resistant Staphylococcus aureus (MRSA) and device-related infections.<\/p>\n


\n\t\u201cBacteria cause major issues in the urinary tract, especially for women,\u201d Rowley said. \u201cIn many patients we see recurring infections because the bacteria are persistent and resistant to antibiotics.\u201d<\/p>\n


\n\tBut Rowley said his laboratory has taken a step toward understanding molecules that could provide at least part of the answer to the problem of antibiotic resistance.<\/p>\n


\n\tThe typical course of treatment for urinary tract infections is antibiotics.<\/p>\n


\n\t\u201cThey clear out most of the infection, which is commonly caused by E. coli bacteria,\u201d Rowley said. \u201cBut some bacteria remain shielded or protected by biofilms. Since these bacteria remain, they re-seed the infection.\u201d<\/p>\n


\n\tBiofilms are groups of microorganisms in which cells stick to each other on a surface.<\/p>\n


\n\tRowley\u2019s research found that a class of complex carbohydrates, called oligosaccharides, could inhibit biofilms formed by E. coli.<\/p>\n


\n\t\u201cWe may be able to pair the biolfilm inhibitors with antibiotics for more effective treatment,\u201d he said.<\/p>\n


\n\tRowley\u2019s paper acknowledges the extensive studies on the role of cranberry phenolics (the anti-oxidant compounds that give cranberries their color) and their role in combating urinary tract infections. However, complex carbohydrates have been studied less extensively. <\/p>\n


\n\tRowley, who originally came to the University to study drugs from the sea and investigate how to decrease antibiotic resistance using marine molecules, said he is generally interested in discovering molecules in nature that can target antibiotic resistance.<\/p>\n


\n\t\u201cWe still don\u2019t fully understand how cranberries exert their effects,\u201d Rowley said. \u201cStudies show phenolics have a benefit, but we don\u2019t know which ones or how they work.<\/p>\n


\n\u201cBut we are looking at a completely different subset of the molecules that you would find in cranberries. Our results show that they have been overlooked and deserve some attention. \u201c<\/p>\n


\nRowley said complex carbohydrates are important because they are digested in the small and large intestines and interact with bacteria like E. coli.<\/p>\n


\n\u201cThe cranberry is a specialty crop cultivated only in certain regions like New England. We are glad to be part of this research and reinforce what people have known for some time. If you drink cranberry juice, it is good for you.\u201d<\/div>\n","protected":false},"excerpt":{"rendered":"

Laboratory tests at College of Pharmacy show antibiotic treatment enhanced KINGSTON, R.I. \u2013 October 15, 2015 \u2013 A 溏心vlog免费B站 researcher and his team in the College of Pharmacy have found that a class of complex carbohydrates could enhance treatment of urinary tract infections. Biomedical Science Professor David Rowley\u2019s findings appear […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[],"class_list":["post-57632","post","type-post","status-publish","format-standard","hentry","category-archives"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/posts\/57632","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/comments?post=57632"}],"version-history":[{"count":0,"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/posts\/57632\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/media?parent=57632"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/categories?post=57632"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.uri.edu\/news\/wp-json\/wp\/v2\/tags?post=57632"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}