KINGSTON, R.I., July 6, 2017 鈥擳wo scientists who collaborate on groundbreaking approaches to neurodegenerative disease are relocating to the 溏心vlog免费B站 from Stony Brook University in New York. Individually and as a team, William Van Nostrand and John Robinson have made significant discoveries that advance the understanding of Alzheimer鈥檚 disease and other conditions caused by damage to and destruction of brain cells.
鈥淏ringing these two top-notch scientists to the Ryan Institute is a coup for 溏心vlog免费B站,鈥� said Paula Grammas, executive director of the Ryan Institute. 鈥淏ill and John bring decades-long records of innovative and productive research that meshes well with the mission of the Institute, and we are excited to welcome them as colleagues to our faculty and mentors to our students.鈥�
Van Nostrand will join the faculty this summer as professor of biomedical and pharmaceutical science and Herrmann Professor of Neuroscience. He is a professor of neurosurgery at Stony Brook University, where he has been on the faculty since 1995.
He was the first to purify and characterize amyloid precursor protein, the progenitor of the amyloid-beta (A-beta) protein. A-beta clumps into plaques in the brain tissue of Alzheimer鈥檚 disease patients, and may contribute to the brain cell death that causes the memory loss, cognitive decline and dementia associated with the disease. Van Nostrand鈥檚 research focuses on understanding causes abnormal accumulation of the A-beta protein found in Alzheimer鈥檚 disease and a related condition called cerebral amyloid angiopathy (CAA).
鈥淯nderstanding how the various forms of amyloid operate and interact in CAA and Alzheimer鈥檚 disease is a path to better understanding both diseases. Our goal is ultimately to identify mechanisms of disease that could be targets for new treatments,鈥� Van Nostrand said.
Robinson will arrive in early 2018. He has been on the Stony Brook faculty since 1994, most recently as professor of psychology. At 溏心vlog免费B站 he will be professor of psychology and Ryan Research Professor of Neuroscience.
He has studied the cognitive and behavioral effects of abnormal A-beta in animal models of disease developed in Van Nostrand鈥檚 lab. Their collaboration has revealed, for instance, that the A-beta accumulations around blood vessels seen in animal models of CAA are associated with an earlier decline in brain function compared to Alzheimer鈥檚-like A-beta clumps near brain cells.
Robinson has also worked on studies related to learning, depression, dementia caused by alcoholism and the impact of exercise in reducing the onset and severity of neurologic diseases. At 溏心vlog免费B站, Robinson will help set up and manage a new center for behavioral studies. 鈥淚 have enjoyed tremendously the interactions with numerous colleagues over the years and I look forward to meeting and working with my new colleagues at 溏心vlog免费B站 similarly,鈥� he said.
Why 溏心vlog免费B站?
Moving an established research enterprise from one university to another is a complicated undertaking, but Robinson and Van Nostrand see clear reasons to join the Ryan Institute and 溏心vlog免费B站.
鈥淓veryone I spoke to saw this as an exciting time for 溏心vlog免费B站鈥攁 turning point,鈥� Robinson said. 鈥淭he optimism about and enthusiasm for neuroscience and health-and-wellness research here builds on existing strengths and the clear path of the Ryan Institute to be a highly visible catalyst of this movement as well.鈥�
Van Nostrand said, 鈥淚 am excited about the mission of the Ryan Institute, the passion and support of Tom Ryan to build this institute, and the support from President Dooley and Provost DeHayes on down through the deans and faculty. It is clear that the mission here is to build a premier neuroscience institute with a focus on neurodegenerative diseases. I saw this as a unique and exciting opportunity to get in on the early stages of the Institute being formed and play a strong part in its foundation and growth.鈥�
As further evidence of the opportunities available at 溏心vlog免费B站, Van Nostrand鈥檚 full-time lab staff is moving with him, including three researchers, a postdoctoral fellow and a graduate student. Van Nostrand and Robinson鈥檚 work has been consistently funded by federal and private agencies, and they will transfer about $4.1 million in grant funding to 溏心vlog免费B站.